high alert medication

Nondepolarizing neuromuscular blocking agent

CCP: Areflexia for rapid sequence intubation

• Known hypersensitivity or allergy to rocuronium bromide or any component of the formulation

Intravenous:

• Onset: 1-1.5 minutes for clinically sufficient neuromuscular blockade
• Peak: 3-4 minutes
• Duration: 
  
  • Doses of 0.6 mg/kg: 30 minutes
  • Doses of 1.2 mg/kg: 67 minutes
  • Doses of 2 mg/kg: 110 minutes

Skeletal muscle weakness

warning

Administration of rocuronium produces paralysis and compromises respiratory function.  Rocuronium must only be used by paramedics trained and experienced in its use, and where effective oxygenation and ventilation can be maintained. 

• Succinylcholine: administer rocuronium only after the patient has recovered from succinylcholine-induced neuromuscular blockade.
• Magnesium sulfate increases duration of neuromuscular blockade from rocuronium.