Antiemetic

ACP: Relief of moderate to severe nausea and vomiting

• Known allergy or hypersensitivity to ondansetron
• Congenital long QT syndrome

Parenteral:

• Onset: 15-30 minutes
• Peak: 30 minutes (IM)
• Duration: > 5 hours

• Hypotension
• Depression or agitation

Carefully assess patients prior to administering ondansetron.  Evaluate the type and intensity of the nausea, as well as the efficacy of relief following administration.  Closely monitor patients for signs of respiratory depression or CNS effects, particularly in elderly patients or those with hepatic or renal impairment.