Epinephrine Infusions

Infusion Pumps

Adult

Standard solution concentrations:

• 4 mcg/mL: dilute 1mg in 250 mL NS
• 12 mcg/mL: dilute 3 mg in 250 mL NS

Pediatric

Standard solution concentrations:

• 4mcg/mL: dilute 1mg in 250mL NS
• 25 mcg/mL: dilute 1.25mg in 50mL NS

Mixing for IV direct for hypotension/shock

Adult and pediatric dosing

Concentration: 10mcg/mL : dilute 0.1mg in 9mL of NS

Process:

• Withdraw 0.1mg (1mL) of 1mg/10mL prefilled syringe in 10mL syringe
• Dilute with 9mL of NS

Drip Sets

It is suggested to set up infusion with pump rather than drip set. If pump delay is a concern, consider bolus doses of phenylephrine or epinephrine to bridge until pump set up complete.