CCP: Anxiety, procedural sedation, short-term amnesia, status epilepticus
CCP: Short-term amnesia
CCP: Status Epilepticus
CCP: Procedural sedation
CCP: Status epilepticus
CCP: Anxiety/Amnesia/Procedural sedation
Sedative hypnotic that enhances the major inhibitory neurotransmitter gamma-aminobutyric acid (GABA) by binding to the benzodiazepine receptor. Lorazepam may depress all levels of the CNS, including limbic and reticular formation.
Onset: 1-3 minutes IV
Duration: up to 8 hours
Peak plasma time: 2 hours
Half-life: 14 hours in adults, 18 hours in children 2-12, adolescents 28 hours
Symptomatic relief and support.