High alert medication
Controlled and targeted substance
Opioid analgesic
PCFP/ACP: Moderate to severe pain
PCFP/ACFP/CCP: Moderate to severe pain (infusion)
Contraindications:
Caution:
PCFP/ACP: Moderate to Severe Pain (E08: Pain Management)
Once initial pain control is achieved, consider multimodal analgesia to support pain control
CliniCall consultation required prior to administration of higher doses
PCFP: CCP-A Consultation Required
PCFP/ACFP/CCP: Moderate to severe pain (infusion)
PCFP: CCP-A Consultation Required
NB: If vascular access is unavailable, the preferred route of administration for fentanyl is intranasal – intramuscular absorption rates are inconsistent in children.
PCFP/ACP: Moderate to Severe Pain (E08: Pain Management)
Fentanyl is preferred over ketamine. Once initial pain control is achieved, consider multimodal analgesia to support pain control.
PCFP: CCP-A Consultation Required
PCFP/ACFP/CCP: Moderate to Severe Pain (infusion)
PCFP: CCP-A Consultation Required
Adult Standard Concentrations:
Inhibits ascending pain pathways in the central nervous system, altering pain perception by binding to opiate receptors, producing analgesia and euphoria.
IV/IO
IN/IM
• Respiratory depression
• Nausea and vomiting
• Hypotension
• Bradycardia or tachycardia
• Hypotension/hypertension
• Hallucinations
• Anxiety
• Seizures
Provide airway management and ventilatory support. Consider the use of naloxone to reverse opioid intoxication. Naloxone should be used judiciously in patients on long-term opioid therapy to avoid precipitating acute withdrawal syndrome.
See Naloxone guideline.
Concomitant use of benzodiazepines or other central nervous system depressants can lead to significant sedation and respiratory depression.