Jennie Helmer, Jade Munro, Adam Greene, Scott Haig, and Tim Makrides
This practice guideline contains changes related to COVID-19.
Sudden cardiac arrest (SCA) and sudden cardiac death (SCD) refer to the sudden cessation of cardiac activity and subsequent hemodynamic collapse. Victims of SCA manifest one of four electrical rhythms: ventricular fibrillation (VF), pulseless ventricular tachycardia (pVT), pulseless electrical activity (PEA), and asystole.
Ventricular fibrillation represents a disorganized electrical activity in the ventricles. Pulseless ventricular tachycardia is an organized electrical activity of the ventricles; neither VF nor pVT have any meaningful cardiac output. Pulseless electrical activity, as a term, encompasses a heterogeneous group of organized electrical rhythms that are associated with either an absence of mechanical activity, or mechanical activity that is insufficient to generate a detectable pulse. Asystole (more specifically ventricular asystole) represents the absence of detectable ventricular electrical activity, with or without atrial electrical activity.
Survival from these rhythms requires both effective basic life support (BLS) and a system of advanced cardiovascular life support (ACLS) with integrated post-cardiac arrest care. An understanding of the importance of diagnosing and treating underlying causes is fundamental to the management of all cardiac arrest rhythms. During a cardiac arrest, paramedics and EMRs/FRs should apply a systematic approach in searching for any factors that may have caused the arrest, or that may be complicating resuscitation efforts.
High quality continuous CPR
Early rhythm analysis & defibrillation if indicated
All patients in the cardiac arrest period should be treated in place with a consideration for immediate conveyance when reasonable.
Available evidence suggests that several therapies or interventions, which have historically been used in resuscitation, should no longer be used routinely:
Atropine during PEA
Vasopressin (offers no advantage over epinephrine)
Precordial thump (associated with a delay in starting CPR and defibrillation)
Crystalloid infusion outside of specific reversible causes
A rhythm change to one of organized electrical activity on the monitor is not an indicator for paramedics to pause chest compressions and assess for a pulse.
Changes in EtCO2 or signs of life are better indicators of a return of spontaneous circulation.
During cardiac arrest, the provision of high quality CPR and rapid defibrillation are the primary goals. Drug administration is a secondary consideration.
After beginning CPR and attempting defibrillation as required, paramedics can attempt to establish vascular access, either intravenously or intraosseously - this should be performed without interrupting chest compressions
The primary purpose of IV/IO access during cardiac arrest is to provide drug therapy; it is reasonable for providers to establish IO access if IV access is not readily available
If IV or IO access cannot be established, epinephrine, vasopressin, and lidocaine may be administered endotracheally during cardiac arrest
Cardiac arrest resuscitations using tibial IO access appear to lead to worse outcomes when compared to IV access. Research to date demonstrates that drug delivery through IV and humeral IO sites are approximately the same with tibial being significantly worse. Definitive data does not yet exist though, so based on current information, we recommend the following practices:
A proximal IV is the preferred vascular access site for cardiac arrest resuscitation
For cases when an IV cannot be established, humeral IO is the next best option
Tibial IO should only be placed due to failure or delay in obtaining IV or humeral IO access
Consider external jugular cannulation where possible
Cardiac arrests related to opioid overdose are likely to be hypoxic in nature. Effective oxygenation, ventilation, and chest compressions are particularly critical for these patients. Naloxone is unlikely to be beneficial, and its use in cardiac arrest is not supported by current evidence.
Special consideration must be given to hypothermic patients without a pulse. As hypothermia progresses, the patient’s respiratory and heart rate slow significantly. For this reason, breathing and pulse checks must be sufficiently long (60 seconds) to register very slow rates.
“Circum-rescue collapse” is a term that describes a death that occurs shortly before, during, or soon after rescue from exposure to a cold environment, usually cold water immersion. It often presents as an apparently stable, conscious patient who suffers ventricular fibrillation and cardiac arrest shortly thereafter.
A patient with a core body temperature below 30°C will most likely develop arrhythmias with progression to ventricular fibrillation.
Medications are more slowly metabolized in hypothermic patients; limit vasopressors to a maximum of 3 doses; refer to → I01: Hypothermia for additional information
In cases of cardiac arrest where effective ventilation and oxygenation cannot be achieved with an iGel, and where 2 person bag-valve mask technique may not be suitable, tracheal intubation can be considered using video laryngoscopy (VL), when it is safe to do so. Direct laryngoscopy may be required in some cases of foreign body airway obstruction but should otherwise be avoided.
Waveform capnography or capnometry to confirm and monitor ETT placement
Transition to continuous chest compressions with ventilations every 6 seconds once ETT is in place
Vascular access: Consider IV/IO access when appropriate
Consider additional reversible causes such as malignant hyperthermia, complications with anesthesia, and/or auto-PEEP
Consider the use of ultrasound in patients receiving CPR to help assess myocardial contractility and to help identify potentially reversible causes of cardiac arrest such as hypovolemia, pneumothorax, pulmonary thromboembolism, or pericardial tamponade